Download Adaptive Motion Compensation in Radiotherapy by Martin J. Murphy PDF

By Martin J. Murphy

External-beam radiotherapy has lengthy been challenged by way of the easy indisputable fact that sufferers can (and do) movement throughout the supply of radiation. fresh advances in imaging and beam supply applied sciences have made the solution―adapting supply to usual movement―a functional fact. Adaptive movement repayment in Radiotherapy provides the 1st certain remedy of on-line interventional suggestions for movement reimbursement radiotherapy.

This authoritative booklet discusses:

  • Each of the contributing parts of a motion-adaptive procedure, together with aim detection and monitoring, beam edition, and sufferer realignment
  • Treatment making plans concerns that come up whilst the sufferer and inner objective are mobile
  • Integrated motion-adaptive platforms in scientific use or at complex levels of development
  • System regulate services necessary to any treatment gadget working in a near-autonomous demeanour with constrained human interaction
  • Necessary motion-detection technique, repositioning concepts, and techniques to analyzing and responding to focus on stream facts in genuine time

Medical treatment with exterior beams of radiation all started as a two-dimensional expertise in a third-dimensional global. in spite of the fact that, in all yet a constrained variety of eventualities, move introduces the fourth measurement of time to the remedy challenge. Motion-adaptive radiation remedy represents a very 4-dimensional technique to an inherently 4-dimensional challenge. From those chapters, readers will achieve not just an realizing of the technical features and services of movement model but in addition functional medical insights into making plans and conducting a variety of forms of motion-adaptive radiotherapy treatment.

Show description

Read or Download Adaptive Motion Compensation in Radiotherapy PDF

Similar biomedical engineering books

Radiation Biophysics

The foremost booklet on radiation biology / radiation biophysics has been Hall's "Radiobiology for the Radiologist" now in it really is fifth variation. it might be great to have a substitute for this, rather because that one is so weighted towards radiation oncology and radiology. Alpen's "Radiation Biophysics" (1998, second ed.

Stem Cell Engineering: Principles and Practices

Whereas the opportunity of stem cells is famous, their proliferation and differentiation needs to be extra accurately managed to maximise the construction of therapeutically proper cells and for mobile substitute remedies to reduce illness with residual cells that may provide upward push to uncomfortable side effects. How can engineers contribute to deal with those demanding situations?

Functional Nanoparticles for Bioanalysis, Nanomedicine, and Bioelectronic Devices Volume 2

Present purposes of nanotechnology span from new fabrics for strength creation or conversion (including photovoltaics, gasoline cells, and so forth. ), to various client items and novel pharmacological formulations, and extend now broadly to biomedical learn, clinical diagnostics and treatment.

Biomechanics and Motor Control of Human Movement

The vintage ebook on human circulate in biomechanics, newly updatedWidely used and referenced, David Winter’s Biomechanics and Motor regulate of Human circulation is a vintage exam of concepts used to degree and learn all physique events as mechanical platforms, together with such daily events as jogging.

Additional info for Adaptive Motion Compensation in Radiotherapy

Sample text

For example, consider one full breathing cycle. The current end of inspiration state is the 0% phase, the upcoming inspiration state is the 100% phase, and all time points in between them are normalized to this percentage scale. One can design a gate width and location in this phase space. Amplitude gating and phase gating result in similar, although not identical, duty cycle and residual target motion (residual motion within the gate) for perfectly periodic, regular respiration. 1). However, in this case, amplitude gating may force beam delivery at various respiration states with the same amplitude, which may result in different patient configurations from cycle to cycle.

The imaging technique selected for measuring target motion should be capable of resolving either the target directly or a strong surrogate. For targets embedded in the liver, the liver itself or the hemidiaphragm is often a good surrogate. Similarly, for breast tumors, the skin surface or chest wall may be a representative of target motion. For the majority of respiratory sites, 4D computed tomography (4DCT) is the most commonly used method, as it possesses good spatial and temporal resolution for this task and is often capable of resolving the target directly.

In this case, one must define the gate width and location for prospectively gated CT and employ the same gate for delivery. If the same surrogate cannot be used, one must measure the surrogate signal during CT acquisition and determine the gating width and location in the surrogate signal based on the timing of CT acquisition. In addition to the selection of gating width and location, one must choose between amplitude and phase gating. 1). If the surrogate signal is considered a periodic signal, the phase is in the temporal position relative to a reference state.

Download PDF sample

Rated 4.70 of 5 – based on 39 votes