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By Iwao Ojima, James R. McCarthy, John T. Welch

content material: fresh advances within the biomedicinal chemistry of fluorine-containing compounds / Kenneth L. Kirk and Robert Filler --
useful synthesis of enantiopure fluoroamino acids of organic curiosity by way of uneven aldol reactions / V.A. Soloshonok --
Synthesis and incorporation of [alpha]-trifluoromethyl-substituted amino acids into peptides / Beate Koksch, Norbert Sewald, Hans-Dieter Jakubke, and Klaus Burger --
Trifluoromethylated amino alcohols : new artificial ways and medicinal pursuits / Jean-Pierre Bégué and Danièle Bonnet-Delpon --
uneven synthesis of functionalized fluorinated cyclopropanes and its program to fluoromethano amino acids / Takeo Taguchi, Akira Shibuya, and Tsutomu Morikawa --
Synthesis and houses of novel fluoroprostacyclins : powerful and reliable prostacyclin agonists / Yasushi Matsumura, Takashi Nakano, Tomoyuki Asai, and Yoshitomi Morizawa --
education of fluorinated amino acids with tyrosine phenol lyase : results of fluorination on response kinetics and mechanism of tyrosine phenol lyase and tyrosine protein kinase Csk / R.L. VonTersch, F. Secundo, R.S. Phillips, and M.G. Newton --
effective artificial routes to chiral 6-deoxy-6,6,6-trifluorosugars through intramolecular 1,2-O, O-silyl migration / Takashi Yamazaki, Kenji Mizutani, and Tomoya Kitazume --
Fluoroamino acid containing analogues of folic acid and methotrexate / Takashi Tsukamoto, James ok. Coward, and John J. McGuire --
Fluoro-olefin isosteres as peptidomimetics / J.T. Welch, J. Lin, L.G. Boros, B. DeCorte, ok. Bergmann, and R. Gimi --
Molecular layout of fluorine-containing peptide mimetics / Piotr Cieplak, Peter A. Kollman, and Jan P. Radomski --
Mechanistic stories of the prenyl move response with fluorinated substrate analogs / C. Dale Poulter --
Elucidation of the mechanism of inhibition of human immunodeficiency virus 1 protease by means of difluorostatones / D. Schirlin, J.M. Rondeau, B. Podlogar, C. Tardif, C. Tarnus, V. Van Dorsselaer, and R. Farr --
Fluorine-containing peptidomimetics as inhibitors of aspartyl proteases / Hing L. Sham --
Inhibition of ornithine aminotransferase : a brand new goal for healing intervention / J.B. Ducep, okay. Jund, B. Lesur, S. Sarhan, M. Schleimer, P.R. Zimmermann, and N. Seiler --
Fluorinated diet D₃ analog with in vivo anticancer task / Katsuhiko Iseki and Yoshiro Kobayashi --
Syntheses, organic job, and conformational research of fluorine-containing taxoids / Iwao Ojima, Scott D. Kuduk, John C. Slater, Rayomand H. Gimi, Chung Ming solar, Subrata Chakravarty, Michele Ourevitch, Ahmed Abouabdellah, Danièle Bonnet-Delpon, Jean-Pierre Bégué, Jean M. Veith, Paula Pera, and Ralph J. Bernacki --
layout of a fluoro-olefin cytidine nucleoside as a bioprecursor of a mechanism-based inhibitor of ribonucleotide reductase / James R. McCarthy, Prasad S. Sunkara, Donald P. Matthews, Alan J. Bitonti, Esa T. Jarvi, Jeffrey S. Sabol, Robert J. Resvick, Edward W. Huber, Wilfred A. van der Donk, Guixue Yu, and JoAnne Stubbe --
Synthesis and organic job of 2',2'-difluorodeoxycytidine (gemcitabine) / L.W. Hertel, J.S. Kroin, C.S. Grossman, Gerald B. Grindey, A.F. Dorr, A.M.V. Storniolo, W. Plunkett, V. Gandhi, and P. Huang --
Fluorinated sugars as probes of glycosidase mechanisms / Mark Namchuk, Curtis Braun, John D. McCarter, and Stephen G. Withers --
¹⁹F-labeled amino acids as structural and dynamic probes in membrane-associated proteins / Zhen-Yu solar, E. Ann Pratt, and Chien Ho --
Fluorinated amino acids in nerve structures / Kenneth L. Kirk and Jun-Ying Nie --
¹⁸F-labeled tracers for positron emission tomography stories within the neurosciences / Yu-Shin Ding and Joanna S. Fowler.

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Ser. , 1988. 5. Selective Fluorination in Organic and Bioorganic Chemistry, Welch, J. T. ; ACS Symp. Ser. , 1991. 6. Welch, J. ; Eswarakrishnan, S. Fluorine in Bioorganic Chemistry; John Wiley & Sons: New York, 1991. 7. ; Yagupolskii, L. ; Elsevier: Amsterdam, 1993. 8. Fluorine-containing Amino Acids. Synthesis and Properties; Kukhar, V. ; Soloshonok, V. ; John Wiley & Sons: Chichester, 1994. 9. Walsh, C. Tetrahedron 1982, 38, 871. 10. Resnati, G. Tetrahedron 1993, 42, 9385. 11. ; Soloshonok, V.

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